Separation of non-electrolytes and electrolytes: These processes use cation exchange resins and anion exchange resins to separate the non-electrolytes(various impurities existing in cation/anion form) from the electrolytes(such as starch sugar). This process includes the refining of starch sugar, sugar refining, sorbitol refining, glycerin refining, and gelatin refining. 

Separation of amphoteric electrolytes: Ion exchange resins are used to separate/refine certain amino acids and antibiotics; using that certain amphoteric electrolytes dissociates in specific pH range. These include the separation/refining of Lysine and Nucleic Acids. Also, Arginine can be separated by the ion-exclusion chromatography principle at isoelectric points pH range. Amino acids that have non-polar groups can be separated at isoelectric points with the use of TRILITE synthetic adsorbents. This includes the L-isoleucine separation/refining process.

 Separation by the difference of molecular weight, hydrologic properties